The menopausal transition, or perimenopause, is characterized by menstrual irregularities,\nvasomotor symptoms, sleep disturbances, mood symptoms, and urogenital tract atrophy. These\nchanges can also affect the quality of life and oneâ??s self-esteem. Hormone replacement therapy\n(HRT) is considered the best option to achieve therapeutic relief of different menopausal symptoms\nbut is usually restricted to moderate or severe symptoms. Moreover, many women refuse HRT for\na variety of reasons concerning the fear of cancer and other adverse effects. According to these\nconsiderations, new topics are emerging: Dissatisfaction with drug costs and conventional\nhealthcare, desire for personalized medicines, and the public perception that â??natural is goodâ?. In\nthis context, nonhormonal therapies are mostly evolving, and it is not unusual that women often\nrequest a â??naturalâ? approach for their symptoms. The aim of this study is to investigate\nnonhormonal therapies that have been identified to reduce the menopausal symptoms.
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